BDBM648180 US20240025922, Example 148

SMILES Cc1c2NCCOc2ncc1N1CCc2cnc(Nc3ccc(CC#N)cc3)nc2C1

InChI Key InChIKey=UNZQKCWZAYIEIY-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 648180   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Merck Patent

US Patent

LigandBDBM648180(US20240025922, Example 148)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:A recombinant fusion protein consisting of full-length human HPK1 (MAP4K1) with an N-terminal Glutatione S-transferase (GST) tag was produced in inse...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/19/2024
Entry Details
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