BDBM648197 US20240025922, Example 165::synthesis of compound 2-{4-[(7-{8-methyl-1H,2H,3H-pyrido[2,3-b][1,4]oxazin-7-yl}-5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-2-yl)amino]phenyl}-1-[3-(morpholin-4-yl)azetidin-1-yl]ethan-1-one

SMILES Cc1c2NCCOc2ncc1N1CCc2cnc(Nc3ccc(CC(=O)N4CC(C4)N4CCOCC4)cc3)nc2C1

InChI Key InChIKey=MUIWGDRPTOTZPO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 648197   

LigandPNGBDBM648197(US20240025922, Example 165 | synthesis of compound...)
Affinity DataIC50: 100nMAssay Description:A recombinant fusion protein consisting of full-length human HPK1 (MAP4K1) with an N-terminal Glutatione S-transferase (GST) tag was produced in inse...More data for this Ligand-Target Pair
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Date in BDB:
3/19/2024
Entry Details
US Patent