BDBM648198 US20240025922, Example 168::synthesis of compound imino(methyl)(3-((7-(8-methyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-7-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)amino)benzyl)-16-sulfanone

SMILES Cc1c2NCCOc2ncc1N1CCc2cnc(Nc3cccc(CS(C)(=N)=O)c3)nc2C1

InChI Key InChIKey=MZAMIVVZFCTZAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 648198   

LigandPNGBDBM648198(US20240025922, Example 168 | synthesis of compound...)
Affinity DataIC50: 100nMAssay Description:A recombinant fusion protein consisting of full-length human HPK1 (MAP4K1) with an N-terminal Glutatione S-transferase (GST) tag was produced in inse...More data for this Ligand-Target Pair
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Date in BDB:
3/19/2024
Entry Details
US Patent