BDBM648207 US20240025922, Example 177::synthesis of compound 7-{8-chloro-1H,2H,3H-pyrido[2,3-b][1,4]oxazin-7-yl}-N-[4-(methanesulfonylmethyl)-3-methylphenyl]-5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-2-amine

SMILES Cc1cc(Nc2ncc3CCN(Cc3n2)c2cnc3OCCNc3c2Cl)ccc1CS(C)(=O)=O

InChI Key InChIKey=LRWHDDJSEDRUMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 648207   

LigandPNGBDBM648207(US20240025922, Example 177 | synthesis of compound...)
Affinity DataIC50: 100nMAssay Description:A recombinant fusion protein consisting of full-length human HPK1 (MAP4K1) with an N-terminal Glutatione S-transferase (GST) tag was produced in inse...More data for this Ligand-Target Pair
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Date in BDB:
3/19/2024
Entry Details
US Patent