BDBM649693 ((1-(3-((3′-((2-chloro-4-((((R)1-ethoxy-3-hydroxy-1-oxopropan-2-yl)amino)methyl)-5-methoxyphenoxy)methyl)-2,2′-dimethyl-[1,1′-biphenyl]-3-yl)oxy)propyl)-1H-1,2,3-triazol-4-yl)methyl)-D-serine ethyl ester::US20240043392, Compound II-21

SMILES CCOC(=O)[C@@H](CO)NCc1cn(CCCOc2cccc(c2C)-c2cccc(COc3cc(OC)c(CN[C@H](CO)C(=O)OCC)cc3Cl)c2C)nn1

InChI Key InChIKey=YUYCHWJMGOTITF-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 649693   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Xi'An Xinton Pharmaceutcal Research

US Patent
LigandPNGBDBM649693(((1-(3-((3′-((2-chloro-4-((((R)1-ethoxy-3-hy...)
Affinity DataIC50: 55nMAssay Description:A negative control, a positive control and drug administration groups were set up, with two duplicate wells in each group. For the positive control g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Xi'An Xinton Pharmaceutcal Research

US Patent
LigandPNGBDBM649693(((1-(3-((3′-((2-chloro-4-((((R)1-ethoxy-3-hy...)
Affinity DataKd:  550nMAssay Description:The test compound was dissolved in DMSO to make a stock solution with a final concentration of 10 mM, then diluted to 1× with 1.05× PBS-P+, and then ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent