BDBM649811 US20240043403, Example 124::US20240043403, Example 48

SMILES CNC[C@H]1CN(CCN1C)c1c(NC(=O)c2ccn(n2)-c2ccnnc2)ccc(C2CCCC2)c1C(F)(F)F

InChI Key InChIKey=UGKNHYXBJDHHDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 649811   

TargetDiacylglycerol kinase delta(Human)
Astellas Pharma

US Patent
LigandPNGBDBM649811(US20240043403, Example 124 | US20240043403, Exampl...)
Affinity DataIC50: 3.80nMAssay Description:To a 384-well plate (Greiner Bio-One Co., Ltd.), 3 μL of a DGK ξ enzyme dissolved in an assay buffer (40 mM Tris-HCl pH 7.5, 10 mM MgCl2, 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetDiacylglycerol kinase delta(Human)
Astellas Pharma

US Patent
LigandPNGBDBM649811(US20240043403, Example 124 | US20240043403, Exampl...)
Affinity DataIC50: 5.80nMAssay Description:To a 384-well plate (Greiner Bio-One Co., Ltd.), 3 μL of a DGK ξ enzyme dissolved in an assay buffer (40 mM Tris-HCl pH 7.5, 10 mM MgCl2, 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent