BDBM6499 4-Anilinoquinazoline deriv. 6b::N-(4-butoxy-3,5-dimethoxyphenyl)-6,7-dimethoxyquinazolin-4-amine

SMILES CCCCOc1c(OC)cc(Nc2ncnc3cc(OC)c(OC)cc23)cc1OC

InChI Key InChIKey=ZHIFGBYEQJQNRE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6499   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM6499(N-(4-butoxy-3,5-dimethoxyphenyl)-6,7-dimethoxyquin...)
Affinity DataIC50: 490nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2005
Entry Details Article
PubMed