BDBM651065 US20240043470, Compound 1-18

SMILES O=C(NC1CCCC1)[C@@H]1Cc2cccc(Oc3cccc(C[C@H](N4CCCC4)C(=O)N[C@@H](CCc4ccccc4)C(=O)N1)c3)c2

InChI Key InChIKey=RQHHLWKKYAPUPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651065   

TargetProteasome subunit beta type-5(Human)
Cornell University

US Patent
LigandPNGBDBM651065(US20240043470, Compound 1-18)
Affinity DataIC50: 572nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent