BDBM651140 US20240043470, Compound 2-03-B

SMILES O=C(CC1NC(=O)CCc2cccc(Oc3ccc(CC(NC1=O)C(=O)NCc1cccc4ccccc14)cc3)c2)N1CCCC1

InChI Key InChIKey=FXEMJBSCIXIFEJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 651140   

TargetProteasome subunit beta type-8(Human)
Cornell University

US Patent
LigandPNGBDBM651140(US20240043470, Compound 2-03-B)
Affinity DataIC50: 960nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
Cornell University

US Patent
LigandPNGBDBM651140(US20240043470, Compound 2-03-B)
Affinity DataIC50: 1.00E+5nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent