BDBM651148 US20240043470, Compound 3-04

SMILES FC(F)(F)CNC(=O)[C@H]1CCCCOc2cccc(C[C@H](N3CCCC3=O)C(=O)N[C@@H](CCc3ccccc3)C(=O)N1)c2

InChI Key InChIKey=QHVWUQNZLCAIFO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 651148   

TargetProteasome subunit beta type-5(Human)
Cornell University

US Patent
LigandPNGBDBM651148(US20240043470, Compound 3-04)
Affinity DataIC50: 1.10E+3nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetProteasome subunit beta type-8(Human)
Cornell University

US Patent
LigandPNGBDBM651148(US20240043470, Compound 3-04)
Affinity DataIC50: 3.28E+4nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent