BDBM651205 US20240043470, Compound 4-13

SMILES Fc1ccccc1CNC(=O)[C@@H]1CCCCCCCCCCC(=O)N[C@@H](CC(=O)N2CCCC2C2CC2)C(=O)N1

InChI Key InChIKey=WXXPNKLCBWYLQB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 651205   

TargetProteasome subunit beta type-8(Human)
Cornell University

US Patent
LigandPNGBDBM651205(US20240043470, Compound 4-13)
Affinity DataIC50: 18nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
Cornell University

US Patent
LigandPNGBDBM651205(US20240043470, Compound 4-13)
Affinity DataIC50: 274nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent