BDBM651728 6-fluoro-N-(2-methoxy- ethyl)-1-methyl-2-((6- (trifluoromethoxy)benzo- [d]oxazol-2-yl)amino)- 1H-benzo[d]imidazole- 5-carboxamide::US20240051952, Example 71

SMILES COCCNC(=O)c1cc2nc(Nc3nc4ccc(OC(F)(F)F)cc4o3)n(C)c2cc1F

InChI Key InChIKey=CYXZPVUHWQZENX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651728   

TargetHeme oxygenase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM651728(US20240051952, Example 71 | 6-fluoro-N-(2-methoxy-...)
Affinity DataEC50:  730nMAssay Description:Measurement of HMOX1 ( HO-1 ) 1. In a polypropylene 384 well plate, human HO-1(after reconstitution in PBS+0.5% Triton+1 mM EDTA) was serially dilute...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent