BDBM651749 1-((3-hydroxyoxetan- 3-yl)methyl)-N-(2- methoxyethyl)-2-((6- (trifluoromethoxy)- benzo[d]oxazol-2-yl)- amino)-1H-benzo[d]- imidazole-5-carbox- amide::US20240051952, Example 94

SMILES COCCNC(=O)c1ccc2n(CC3(O)COC3)c(Nc3nc4ccc(OC(F)(F)F)cc4o3)nc2c1

InChI Key InChIKey=NESDWAJNGLFBOC-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651749   

TargetHeme oxygenase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM651749(US20240051952, Example 94 | 1-((3-hydroxyoxetan- 3...)
Affinity DataEC50:  1.30E+3nMAssay Description:Measurement of HMOX1 ( HO-1 ) 1. In a polypropylene 384 well plate, human HO-1(after reconstitution in PBS+0.5% Triton+1 mM EDTA) was serially dilute...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent