BDBM653640 US11911372, Example 62::US20240277683, Example 62

SMILES Brc1ccc(cc1)-c1cc(NS(=O)(=O)c2ccccc2)no1

InChI Key InChIKey=ICGGRZJLTZPHIB-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 653640   

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653640(US11911372, Example 62 | US20240277683, Example 62)
Affinity DataIC50: 5.26E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT7(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653640(US11911372, Example 62 | US20240277683, Example 62)
Affinity DataIC50: 5.31E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT8(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653640(US11911372, Example 62 | US20240277683, Example 62)
Affinity DataIC50: 1.62E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT5(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653640(US11911372, Example 62 | US20240277683, Example 62)
Affinity DataIC50: 6.83E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT8(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653640(US11911372, Example 62 | US20240277683, Example 62)
Affinity DataIC50: 1.62E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT5(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653640(US11911372, Example 62 | US20240277683, Example 62)
Affinity DataIC50: 6.83E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653640(US11911372, Example 62 | US20240277683, Example 62)
Affinity DataIC50: 5.26E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT7(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653640(US11911372, Example 62 | US20240277683, Example 62)
Affinity DataIC50: 5.31E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent