BDBM656327 US11919855, Name NUCC-0163358::US11919855, Name NUCC-0202826::US11919855, Name NUCC-0202850

SMILES Cc1ccc(O)c(c1)C(=O)NC1CN(Cc2ccccc2C(F)(F)F)C(=O)C1

InChI Key InChIKey=ACGLRHRNOLCYOQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 656327   

TargetHistone-lysine N-methyltransferase EZH2/Polycomb protein EED(Human)
Northwestern University

US Patent
LigandPNGBDBM656327(US11919855, Name NUCC-0202826 | US11919855, Name N...)
Affinity DataIC50: 5.50E+3nMAssay Description:Materials:EZH2 (non-complexed), His-GST-tagsEED, FLAG-tag4× HMT Buffer 2Anti-FLAG AlphaLISA Acceptor BeadsAlphaScreen GSH Donor BeadsAssay Protocol (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase EZH2/Polycomb protein EED(Human)
Northwestern University

US Patent
LigandPNGBDBM656327(US11919855, Name NUCC-0202826 | US11919855, Name N...)
Affinity DataIC50: 5.00E+4nMAssay Description:Materials:EZH2 (non-complexed), His-GST-tagsEED, FLAG-tag4× HMT Buffer 2Anti-FLAG AlphaLISA Acceptor BeadsAlphaScreen GSH Donor BeadsAssay Protocol (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
Go to US Patent

TargetHistone-lysine N-methyltransferase EZH2/Polycomb protein EED(Human)
Northwestern University

US Patent
LigandPNGBDBM656327(US11919855, Name NUCC-0202826 | US11919855, Name N...)
Affinity DataIC50: 5.00E+4nMAssay Description:Materials:EZH2 (non-complexed), His-GST-tagsEED, FLAG-tag4× HMT Buffer 2Anti-FLAG AlphaLISA Acceptor BeadsAlphaScreen GSH Donor BeadsAssay Protocol (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
Go to US Patent