BDBM656461 US11919855, Name NUCC-0226232

SMILES Oc1ccc(cc1C(=O)NC1CCN(Cc2cccc(c2)C(F)(F)F)C1=O)C(F)(F)F

InChI Key InChIKey=ITNHHNGZNYWNJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656461   

TargetHistone-lysine N-methyltransferase EZH2/Polycomb protein EED(Human)
Northwestern University

US Patent
LigandPNGBDBM656461(US11919855, Name NUCC-0226232)
Affinity DataIC50: 5.50E+3nMAssay Description:Materials:EZH2 (non-complexed), His-GST-tagsEED, FLAG-tag4× HMT Buffer 2Anti-FLAG AlphaLISA Acceptor BeadsAlphaScreen GSH Donor BeadsAssay Protocol (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
Go to US Patent