BDBM656470 US11919855, Name NUCC-0226242

SMILES Oc1ccc(cc1C(=O)NC[C@H]1CCC(=O)N1Cc1cccc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=APRKFCUCNYGLMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656470   

TargetHistone-lysine N-methyltransferase EZH2/Polycomb protein EED(Human)
Northwestern University

US Patent
LigandPNGBDBM656470(US11919855, Name NUCC-0226242)
Affinity DataIC50: 5.50E+3nMAssay Description:Materials:EZH2 (non-complexed), His-GST-tagsEED, FLAG-tag4× HMT Buffer 2Anti-FLAG AlphaLISA Acceptor BeadsAlphaScreen GSH Donor BeadsAssay Protocol (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
Go to US Patent