BDBM657091 US11926614, Example 86

SMILES CCOc1ccc(nc1)-c1nnc(n1-c1ccc(C)s1)C12CC(C1)(C2)NC(=O)c1ccnc2cc(F)cnc12

InChI Key InChIKey=CPXAUDRPXZSGLM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 657091   

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Oslo Universitetssykehus

US Patent
LigandPNGBDBM657091(US11926614, Example 86)
Affinity DataIC50: 2.20nMAssay Description:Biochemical IC50 values for the following compounds were determined in accordance with the following protocol (see also Anumala et al., Discovery of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2024
Entry Details
US Patent