BDBM660322 US20240092795, Example 3

SMILES N[C@@H]1CCCC11CCN(CC1)c1cnc(c(O)c1)-c1cccc(Cl)c1Cl

InChI Key InChIKey=ICDFYPLIFBICSQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 660322   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Revolution Medicines

US Patent
LigandPNGBDBM660322(US20240092795, Example 3)
Affinity DataIC50: 740nMAssay Description:The catalytic activity of SHP2 was monitored using the surrogate substrate DiFMUP in a prompt fluorescence assay format.The phosphatase reactions wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
Go to US Patent