BDBM660728 6-((2-oxaspiro[3.3]heptan-6- yl)oxy)-N-(6-chloropyridin-3- yl)isoquinolin-1-amine::US20240101531, Example 113

SMILES Clc1ccc(Nc2nccc3cc(OC4CC5(COC5)C4)ccc23)cn1

InChI Key InChIKey=NMFFGEPWVNGUEG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 660728   

TargetPotassium voltage-gated channel subfamily KQT member 2/3 (Human)
Xenon Pharmaceuticals

US Patent
LigandPNGBDBM660728(6-((2-oxaspiro[3.3]heptan-6- yl)oxy)-N-(6-chloropy...)
Affinity DataEC50: <1.00E+3nMAssay Description:This potassium flux assay employs the cell-permeable, potassium-sensitive dye, IPG-2 AM, to quantify potassium ion flux through potassium channels.In...More data for this Ligand-Target Pair
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Date in BDB:
6/11/2024
Entry Details
US Patent