BDBM661177 6-(1-methyl-1H-pyrazol-3-yl)-2-(4-(4- methyl-4H-1,2,4-triazol-3-yl)piperidin- 1-yl)-3-(6-methylpyridazin-4- yl)benzonitrile::US20240101544, Example 61

SMILES Cc1cc(cnn1)-c1ccc(-c2ccn(C)n2)c(C#N)c1N1CCC(CC1)c1nncn1C

InChI Key InChIKey=VBNBNNUURNEGNS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661177   

TargetGlutaminyl-peptide cyclotransferase(Human)
TBA

US Patent
LigandPNGBDBM661177(US20240101544, Example 61 | 6-(1-methyl-1H-pyrazol...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCT (rhQPCT, R&D Systems) activity were determined using a biochemical fluorescent-based assay. QPCT acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

LigandPNGBDBM661177(US20240101544, Example 61 | 6-(1-methyl-1H-pyrazol...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCTL activity were determined using a biochemical fluorescent-based assay. QPCTL activity was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent