BDBM661179 6-(1-cyclopropyl-1H-pyrazol-4-yl)-3- (6-fluoropyridin-3-yl)-2-(4-(4-methyl- 4H-1,2,4-triazol-3-yl)piperidin-1- yl)benzonitrile::US20240101544, Example 63

SMILES Cn1cnnc1C1CCN(CC1)c1c(ccc(-c2cnn(c2)C2CC2)c1C#N)-c1ccc(F)nc1

InChI Key InChIKey=PNQINQLJNXJNCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661179   

TargetGlutaminyl-peptide cyclotransferase(Human)
TBA

US Patent
LigandPNGBDBM661179(US20240101544, Example 63 | 6-(1-cyclopropyl-1H-py...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCT (rhQPCT, R&D Systems) activity were determined using a biochemical fluorescent-based assay. QPCT acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

LigandPNGBDBM661179(US20240101544, Example 63 | 6-(1-cyclopropyl-1H-py...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCTL activity were determined using a biochemical fluorescent-based assay. QPCTL activity was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent