BDBM661201 3-(6-fluoropyridin-3-yl)-2-(4-(4- methyl-4H-1,2,4-triazol-3-yl)piperidin- 1-yl)-6-(piperazin-1-yl)benzonitrile::US20240101544, Example 85

SMILES Cn1cnnc1C1CCN(CC1)c1c(ccc(N2CCNCC2)c1C#N)-c1ccc(F)nc1

InChI Key InChIKey=IWCWIFSEAREXNR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661201   

TargetGlutaminyl-peptide cyclotransferase(Human)
TBA

US Patent
LigandPNGBDBM661201(US20240101544, Example 85 | 3-(6-fluoropyridin-3-y...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCT (rhQPCT, R&D Systems) activity were determined using a biochemical fluorescent-based assay. QPCT acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

LigandPNGBDBM661201(US20240101544, Example 85 | 3-(6-fluoropyridin-3-y...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCTL activity were determined using a biochemical fluorescent-based assay. QPCTL activity was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent