BDBM661202 3-(6-fluoropyridin-3-yl)-6-(2- methoxyethoxy)-2-(4-(4-methyl-4H- 1,2,4-triazol-3-yl)piperidin-1- yl)benzonitrile::US20240101544, Example 86

SMILES COCCOc1ccc(-c2ccc(F)nc2)c(N2CCC(CC2)c2nncn2C)c1C#N

InChI Key InChIKey=MASPWPSUXMTINJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 661202   

TargetGlutaminyl-peptide cyclotransferase(Human)
TBA

US Patent
LigandPNGBDBM661202(US20240101544, Example 86 | 3-(6-fluoropyridin-3-y...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCT (rhQPCT, R&D Systems) activity were determined using a biochemical fluorescent-based assay. QPCT acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent

LigandPNGBDBM661202(US20240101544, Example 86 | 3-(6-fluoropyridin-3-y...)
Affinity DataIC50: 100nMAssay Description:Compound IC50 values for the inhibition of QPCTL activity were determined using a biochemical fluorescent-based assay. QPCTL activity was measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent