BDBM661363 US20240101559, Compound I-2

SMILES CC(=O)Nc1cc(Oc2ccc3nc(Nc4cccc(c4)C(C)(C)C#N)n4CCCc2c34)ccn1

InChI Key InChIKey=RRNLSANMBMBZBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 661363   

TargetTyrosine-protein kinase JAK2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM661363(US20240101559, Compound I-2)
Affinity DataIC50: 4.07E+3nMAssay Description:The JAK2 Z-Lyte biochemical assay was performed according to manufacturer's instructions (Life Technologies).More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2024
Entry Details
US Patent