BDBM66224 2-(2,5-dimethoxyphenyl)-3-ethanoyl-4-oxidanyl-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one::3-acetyl-2-(2,5-dimethoxyphenyl)-4-hydroxy-1-(3-pyridinylmethyl)-2H-pyrrol-5-one::3-acetyl-2-(2,5-dimethoxyphenyl)-4-hydroxy-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one::4-Acetyl-5-(2,5-dimethoxy-phenyl)-3-hydroxy-1-pyridin-3-ylmethyl-1,5-dihydro-pyrrol-2-one::4-acetyl-5-(2,5-dimethoxyphenyl)-3-hydroxy-1-(3-pyridylmethyl)-3-pyrrolin-2-one::MLS000068410::SMR000011311::cid_645321

SMILES COc1ccc(OC)c(c1)C1C(C(C)=O)C(=O)C(=O)N1Cc1cccnc1

InChI Key InChIKey=QASLCQTYYOBWGT-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 66224   

TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM66224(3-acetyl-2-(2,5-dimethoxyphenyl)-4-hydroxy-1-(pyri...)
Affinity DataEC50: >3.50E+5nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay