BDBM6641 (5E)-5-[(2-methyl-1H-indol-3-yl)methylidene]-2-sulfanylideneimidazolidin-4-one::Thiourea deriv. 8

SMILES Cc1[nH]c2ccccc2c1\C=C1\NC(=S)NC1=O

InChI Key InChIKey=SNLLEQAPNVMOOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6641   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM6641((5E)-5-[(2-methyl-1H-indol-3-yl)methylidene]-2-sul...)
Affinity DataIC50: 1.40E+4nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 45 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2005
Entry Details Article
PubMed