BDBM665638 2-(4-(4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)piperidin-1-yl)phenyl)-1,2,4-triazine-3, 5(2H,4H)-dione::US20240116912, Example 17

SMILES Clc1cccc(Cl)c1-c1noc(C2CC2)c1COC1CCN(CC1)c1ccc(cc1)-n1ncc(=O)[nH]c1=O

InChI Key InChIKey=OVTXNXZXPHHAHI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 665638   

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM665638(US20240116912, Example 17 | 2-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  6.07E+3nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent