BDBM667804 6-(1-(2-Cyanopropan-2-yl)-1H-pyrazol-4-yl)-N-(3-(difluoromethyl)-1-(1-(1-(2-hydroxyacetyl)piperidin-4-yl)azetidin-3-yl)-1H-pyrazol-4-yl)-2-picolinamide::US11958831, Example 43

SMILES CC(C)(C#N)n1cc(cn1)-c1cccc(n1)C(=O)Nc1cn(nc1C(F)F)C1CN(C1)C1CCN(CC1)C(=O)CO

InChI Key InChIKey=XQBXSBMIAQQZTD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 667804   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Artivila (Shenzhen) Innovation Center

US Patent
LigandPNGBDBM667804(6-(1-(2-Cyanopropan-2-yl)-1H-pyrazol-4-yl)-N-(3-(d...)
Affinity DataIC50: 0.970nMAssay Description:The compounds were prepared with DMSO to 100 times the final reaction concentration and diluted to 10 concentrations in sequence at a 3-fold dilution...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2024
Entry Details
Go to US Patent