BDBM66836 MLS001028806::N-(2-chlorobenzyl)-2-[7-keto-3,4-dimethyl-2-(p-tolyl)pyrazolo[3,4-d]pyridazin-6-yl]propionamide::N-[(2-chlorophenyl)methyl]-2-[3,4-dimethyl-2-(4-methylphenyl)-7-oxidanylidene-pyrazolo[3,4-d]pyridazin-6-yl]propanamide::N-[(2-chlorophenyl)methyl]-2-[3,4-dimethyl-2-(4-methylphenyl)-7-oxo-6-pyrazolo[3,4-d]pyridazinyl]propanamide::N-[(2-chlorophenyl)methyl]-2-[3,4-dimethyl-2-(4-methylphenyl)-7-oxopyrazolo[3,4-d]pyridazin-6-yl]propanamide::SMR000629826::cid_20919858

SMILES CC(C(=O)NCc1ccccc1Cl)n1nc(C)c2c(C)n(nc2c1=O)-c1ccc(C)cc1

InChI Key InChIKey=JJJYGHOYKUXTEW-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 66836   

TargetD(3) dopamine receptor(Human)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 66836BDBM66836(US12479838, Compound FOB02-04B)
Affinity DataKi:  282nMAssay Description:Assay Provider: P. Jeffrey Conn Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of novel allosteric modulators of the M1 mus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2026
Entry Details US Patent

TargetD(2) dopamine receptor(Human)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 66836BDBM66836(US12479838, Compound FOB02-04B)
Affinity DataKi:  831nMAssay Description:Assay Provider: P. Jeffrey Conn Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of novel allosteric modulators of the M1 mus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2026
Entry Details US Patent

TargetD(3) dopamine receptor(Human)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 66836BDBM66836(US12479838, Compound FOB02-04B)
Affinity DataKi:  2.90E+3nMAssay Description:Assay Provider: P. Jeffrey Conn Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of novel allosteric modulators of the M1 mus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2026
Entry Details US Patent

TargetD(2) dopamine receptor(Human)
Department Of Health And Human Services

US Patent
LigandChemical structure of BindingDB Monomer ID 66836BDBM66836(US12479838, Compound FOB02-04B)
Affinity DataKi:  7.06E+4nMAssay Description:Assay Provider: P. Jeffrey Conn Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of novel allosteric modulators of the M1 mus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2026
Entry Details US Patent