BDBM670713 4-[[(3R)-1-[(3R)-7-(ethylamino)-5-fluoro-3-methyl-2-oxo-indolin-3-yl]-3-piperidyl]oxy]benzenesulfonyl fluoride and 4-[[(3R)-1-[(3S)-7-(ethylamino)-5-fluoro-3-methyl-2-oxo-indolin-3-yl]-3-piperidyl]oxy]benzenesulfonyl fluoride::US20240140933, Example 3A

SMILES CCNc1cc(F)cc2c1NC(=O)[C@]2(C)N1CCC[C@H](C1)Oc1ccc(cc1)S(F)(=O)=O

InChI Key InChIKey=KVGXQGRDKZLWID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670713   

LigandPNGBDBM670713(4-[[(3R)-1-[(3R)-7-(ethylamino)-5-fluoro-3-methyl-...)
Affinity DataIC50: 77nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
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