BDBM670730 7-(ethylamino)-5-fluoro-3-methyl-3-[(3R)-3-[(6-methylsulfonyl-3-pyridyl)amino]-1-piperidyl]indolin-2-one::US20240140933, Example 20

SMILES CCNc1cc(F)cc2c1NC(=O)C2(C)N1CCC[C@H](C1)Nc1ccc(nc1)S(C)(=O)=O

InChI Key InChIKey=LDVFAVZPTNGBSP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670730   

LigandPNGBDBM670730(7-(ethylamino)-5-fluoro-3-methyl-3-[(3R)-3-[(6-met...)
Affinity DataIC50: 82nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
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