BDBM670745 N-[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo-indolin-3-yl]-3-piperidyl]-3,5-difluoro-4-hydroxy-benzamide::US20240140933, Example 35

SMILES CCNc1cc(F)cc2c1NC(=O)C2(C)N1CCC[C@H](C1)NC(=O)c1cc(F)c(O)c(F)c1

InChI Key InChIKey=ACEKRWNWDBMSFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670745   

LigandPNGBDBM670745(N-[(3R)-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo-...)
Affinity DataIC50: 65nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
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