BDBM670767 4-[2-[(3R,4R)-3-acetamido-1-[7-(ethylamino)-5-fluoro-3-methyl-2-oxo-indolin-3-yl]-4-piperidyl]phenoxy]benzamide::US20240140933, Example 57

SMILES CCNc1cc(F)cc2c1NC(=O)C2(C)N1CC[C@@H]([C@H](C1)NC(C)=O)c1ccccc1Oc1ccc(cc1)C(N)=O

InChI Key InChIKey=QATWPWXGLHUCQW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 670767   

LigandPNGBDBM670767(4-[2-[(3R,4R)-3-acetamido-1-[7-(ethylamino)-5-fluo...)
Affinity DataIC50: 34nMAssay Description:The inhibitory potency of compounds of PDHK1 activity was determined in an enzymatic assay. Pyruvate dehydrogenase complex (PDHc) is an enzyme that c...More data for this Ligand-Target Pair
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Date in BDB:
7/25/2024
Entry Details
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