BDBM67109 2-(4-besylpiperazino)-N-[4-chloro-3-(trifluoromethyl)phenyl]-2-phenyl-acetamide::2-[4-(benzenesulfonyl)-1-piperazinyl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-2-phenylacetamide::2-[4-(benzenesulfonyl)piperazin-1-yl]-N-[4-chloro-3-(trifluoromethyl)phenyl]-2-phenylacetamide::N-[4-chloranyl-3-(trifluoromethyl)phenyl]-2-phenyl-2-[4-(phenylsulfonyl)piperazin-1-yl]ethanamide::SR-03000000778-1::cid_4852241

SMILES O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc4c(n3)C(N3CCC3)CC43CCOCC3)c21

InChI Key InChIKey=PXFSNHKBZMNYHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 67109   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Betta Pharmaceuticals Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 67109BDBM67109(US20250361241, Compound 39)
Affinity DataIC50: 2.78nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2026
Entry Details Article
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Betta Pharmaceuticals Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 67109BDBM67109(US20250361241, Compound 39)
Affinity DataIC50: 3.70nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2026
Entry Details Article
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Betta Pharmaceuticals Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 67109BDBM67109(US20250361241, Compound 39)
Affinity DataIC50: 88.2nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2026
Entry Details Article
US Patent