BDBM67140 6,7-dimethoxy-3-[[3-(2-methoxyphenyl)-1,2-oxazol-5-yl]methyl]-2-(morpholin-4-ylmethylidene)-1H-quinazolin-4-one::6,7-dimethoxy-3-[[3-(2-methoxyphenyl)-5-isoxazolyl]methyl]-2-(4-morpholinylmethylidene)-1H-quinazolin-4-one::6,7-dimethoxy-3-[[3-(2-methoxyphenyl)isoxazol-5-yl]methyl]-2-(morpholinomethylene)-1H-quinazolin-4-one::SR-03000001033-1::cid_44202998

SMILES COc1cc2nc(CN3CCOCC3)n(Cc3cc(no3)-c3ccccc3OC)c(=O)c2cc1OC

InChI Key InChIKey=YALFILZXFILKCV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 67140   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Betta Pharmaceuticals Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 67140BDBM67140(US20250361241, Compound 87)
Affinity DataIC50: 5.12nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2026
Entry Details ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Betta Pharmaceuticals Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 67140BDBM67140(US20250361241, Compound 87)
Affinity DataIC50: 724nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2026
Entry Details ArticlePubMed