BDBM673629 (1r,2′S,4S)-4-(3-chloroanilino)-2′-[(2R)-2-methyl-3-{[(5R)-5-methyl-5,6,7,8-tetrahydroquinolin-4-yl]oxy}propyl]-6′-propoxy-2′,3′-dihydrospiro[cyclohexane-1,1′-indene]-4-carboxylic acid::US20240150293, Example 787

SMILES CCCOc1ccc2C[C@H](C[C@@H](C)COc3ccnc4CCC[C@@H](C)c34)[C@]3(CC[C@](CC3)(Nc3cccc(Cl)c3)C(O)=O)c2c1

InChI Key InChIKey=QQXWIHAPTRNTBR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673629   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
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US Patent
LigandPNGBDBM673629(US20240150293, Example 787 | (1r,2′S,4S)-4-(...)
Affinity DataKi:  0.0570nMAssay Description:The addition of a compound which binds competitively to the same site as the peptide will result in an increase in the fluorescence intensity of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent