BDBM673674 (1r,2′S,4S)-4-(3-chloroanilino)-6′-(1-hydroxyethyl)-2′-[(2R)-2-methyl-3-{[(5R)-5-methyl-5,6,7,8-tetrahydroquinolin-4-yl]oxy}propyl]-2′,3′-dihydrospiro[cyclohexane-1,1′-indene]-4-carboxylic acid, diastereoisomer 2::US20240150293, Example 860

SMILES C[C@@H](COc1ccnc2CCC[C@@H](C)c12)C[C@H]1Cc2ccc(cc2[C@@]11CC[C@](CC1)(Nc1cccc(Cl)c1)C(O)=O)[C@@H](C)O

InChI Key InChIKey=KMLWFNWXSFJKII-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673674   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
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US Patent
LigandPNGBDBM673674(US20240150293, Example 860 | (1r,2′S,4S)-4-(...)
Affinity DataKi:  0.0190nMAssay Description:The addition of a compound which binds competitively to the same site as the peptide will result in an increase in the fluorescence intensity of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent