BDBM673680 Example 866A methyl (1s,4s)-2′-bromo-4-[(3-chlorophenyl)(trifluoroacetyl)amino]-6′-(2-hydroxypropan-2-yl)spiro[cyclohexane-1,1′-indene]-4-carboxylate::US20240150293, Example 866

SMILES COC(=O)[C@]1(CC[C@@]2(CC1)C(C[C@@H](C)COc1ccnc3CCC[C@@H](C)c13)=Cc1ccc(cc21)C(C)(C)OC)Nc1cccc(Cl)c1

InChI Key InChIKey=LOXORJHMUOLLBT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673680   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
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US Patent
LigandPNGBDBM673680(US20240150293, Example 866 | Example 866A methyl (...)
Affinity DataKi:  0.0210nMAssay Description:The addition of a compound which binds competitively to the same site as the peptide will result in an increase in the fluorescence intensity of the ...More data for this Ligand-Target Pair
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Date in BDB:
8/9/2024
Entry Details
US Patent