BDBM673702 Example 919A methyl (1r,4R)-4-(3-chloroanilino)-6′-(hydroxymethyl)-2′-{(2R)-3-[(4-methoxyphenyl)methoxy]-2-methylpropyl}spiro[cyclohexane-1,1′-indene]-4-carboxylate::US20240150293, Example 919

SMILES COCc1ccc2C[C@H](C[C@@H](C)COc3ccnc4CCC[C@@H](C)c34)[C@]3(CC[C@](CC3)(Nc3cccc(Cl)c3)C(O)=O)c2c1

InChI Key InChIKey=WMRPEEKQYGTVHY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673702   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
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US Patent
LigandPNGBDBM673702(US20240150293, Example 919 | Example 919A methyl (...)
Affinity DataKi:  0.0270nMAssay Description:The addition of a compound which binds competitively to the same site as the peptide will result in an increase in the fluorescence intensity of the ...More data for this Ligand-Target Pair
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Date in BDB:
8/9/2024
Entry Details
US Patent