BDBM673732 (1r,4S,6′S)-4-(3-chloroanilino)-2′-methyl-6′-[(2R)-2-methyl-3-{[(5R)-5-methyl-5,6,7,8-tetrahydroquinolin-4-yl]oxy}propyl]-6′,7′-dihydro-2′H-spiro[cyclohexane-1,5′-indeno[5,6-d][1,3]dioxole]-4-carboxylic acid, diastereoisomer 2::US20240150293, Example 966

SMILES C[C@@H](COc1ccnc2CCC[C@@H](C)c12)C[C@H]1Cc2cc3OC(C)Oc3cc2[C@@]11CC[C@](CC1)(Nc1cccc(Cl)c1)C(O)=O

InChI Key InChIKey=WYSPPJDLAAOPHR-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673732   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM673732(US20240150293, Example 966 | (1r,4S,6′S)-4-(...)
Affinity DataKi:  0.0270nMAssay Description:The addition of a compound which binds competitively to the same site as the peptide will result in an increase in the fluorescence intensity of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent