BDBM673755 (1r,4S,8′S)-4-(3-chloroanilino)-8′-[(2R)-2-methyl-3-{[(5R)-5-methyl-5,6,7,8-tetrahydroquinolin-4-yl]oxy}propyl]-3′-propyl-3′,4′,8′,9′-tetrahydro-2′H-spiro[cyclohexane-1,7′-indeno[5,6-b][1,4]dioxepine]-4-carboxylic acid, diastereoisomer 2::US20240150293, Example 991

SMILES CCC[C@H]1COc2cc3C[C@H](C[C@@H](C)COc4ccnc5CCC[C@@H](C)c45)[C@]4(CC[C@](CC4)(Nc4cccc(Cl)c4)C(O)=O)c3cc2OC1

InChI Key InChIKey=UXBKLUBDUYSOQD-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 673755   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
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US Patent
LigandPNGBDBM673755(US20240150293, Example 991 | (1r,4S,8′S)-4-(...)
Affinity DataKi:  0.0760nMAssay Description:The addition of a compound which binds competitively to the same site as the peptide will result in an increase in the fluorescence intensity of the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
US Patent