BDBM673767 3-(4-(3,5-Dimethyl-1H-pyrazol-4-yl)piperazin-1-yl)-4-methoxybenzoic Acid::US20240150297, Compound 18c

SMILES COc1ccc(cc1N1CCN(CC1)c1c(C)n[nH]c1C)C(O)=O

InChI Key InChIKey=DVEBKCRFLRYCNM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 673767   

TargetTransthyretin (TTR)(Human)
Columbia University

US Patent
LigandPNGBDBM673767(US20240150297, Compound 18c | 3-(4-(3,5-Dimethyl-1...)
Affinity DataIC50: 300nMAssay Description:Compound binding to TTR was assessed in the fluorescence polarization assay. The assay measured competitive displacement of the fluorescent probe, FI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
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TargetAT-rich interactive domain-containing protein 4A(Human)
Columbia University

US Patent
LigandPNGBDBM673767(US20240150297, Compound 18c | 3-(4-(3,5-Dimethyl-1...)
Affinity DataIC50: 3.00E+3nMAssay Description:In vitro binding of compounds to RBP4. Compound binding to RBP4 was assessed in the radiometric scintillation proximity (SPA) assay that was previous...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent