BDBM674211 3,5-difluoro-4- hydroxy-N- ({(1r,4r)-4-[6-(1- methyl-2,3-dihydro- 1H-imidazo[1,2-b] pyrazol-7-yl)-2H- indazol-2-yl] cyclohexyl}methyl) benzamide::US20240150334, Example 41

SMILES CN1CCn2ncc(c12)-c1ccc2cn(nc2c1)[C@H]1CC[C@H](CNC(=O)c2cc(F)c(O)c(F)c2)CC1

InChI Key InChIKey=DGVVBYWIVOAQAD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 674211   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Pfizer

US Patent
LigandPNGBDBM674211(3,5-difluoro-4- hydroxy-N- ({(1r,4r)-4-[6-(1- meth...)
Affinity DataIC50: 3.40nMAssay Description:HSD17B13 uses the oxidized form of nicotinamide adenine dinucleotide (NAD+) as a cofactor during metabolism of beta-estradiol (substrate), converting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2024
Entry Details
Go to US Patent