BDBM674477 2-(2-(3-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naphthyridine-6-formamido) Acetic Acid::US11981669, Compound Link-126

SMILES OC(=O)CNC(=O)c1nc(Cl)c2nc(Oc3cccc(Cl)c3)ccc2c1O

InChI Key InChIKey=OCOXTBFRGGFOMM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 674477   

TargetCytochrome P450 3A4(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674477(2-(2-(3-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674477(2-(2-(3-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674477(2-(2-(3-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674477(2-(2-(3-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang)

US Patent
LigandPNGBDBM674477(2-(2-(3-chlorophenoxy)-5-hydroxy-8-chloro-1,7-naph...)
Affinity DataIC50: 5.00E+4nMAssay Description:The compounds of the present disclosure were subjected to the CYP450 enzyme inhibition assay. The experimental results showed that the compounds of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2024
Entry Details
US Patent