BDBM67558 (Described as Example 46 in WO2005/113580): (3S)-3-({N-[(4-methoxy-1H-indol-2-yl)carbonyl]-L-leucyl}amino)-2-oxo-4-[(3S)-2-oxopyrrolidin-3-yl]butyl 2,6-dichlorobenzoate::US12485157, Example 9

SMILES COc1cccc2[nH]c(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C[C@@H]3CCNC3=O)C(=O)Oc3c(Cl)cccc3Cl)cc12

InChI Key InChIKey=LWJOBDRSLHPYPD-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 67558   

TargetReplicase polyprotein 1a(2019-nCoV)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 67558BDBM67558((Described as Example 46 in WO2005/113580): (3S)-3...)
Affinity DataKi:  0.300nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2026
Entry Details Article
US Patent