BDBM67566 US12486251, Example 17

SMILES CNC(=O)c6cc2ccc(C1CCOCC1)cc2c(N5CCCc4cc(c3cnn(C)c3)c(C(F)F)cc45)n6

InChI Key InChIKey=AVAADMXSZRMYBG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 67566   

TargetCREB-binding protein(Human)
Pharmablock Sciences (Nanjing)

US Patent
LigandChemical structure of BindingDB Monomer ID 67566BDBM67566(US12486251, Example 17)
Affinity DataIC50: 12nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2026
Entry Details Article
US Patent