BDBM6765 3-(6-fluoro-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::bis-indolylmaleimide deriv. 8b

SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c[nH]c3cc(F)ccc23)c2ccccc12

InChI Key InChIKey=XGGWHSPLTSVHGO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 6765   

LigandPNGBDBM6765(3-(6-fluoro-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-...)
Affinity DataIC50: 840nMpH: 7.0 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6765(3-(6-fluoro-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-...)
Affinity DataIC50: 1.50E+3nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed
LigandPNGBDBM6765(3-(6-fluoro-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-...)
Affinity DataIC50: 1.62E+4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2005
Entry Details Article
PubMed