BDBM676764 US20240166651, Example 5::methyl 2-(4-chloro-2-fluorophenyl)-2-(3-(methyl(7H-

SMILES COC(=O)C(N1CCC(C1)N(C)c1ncnc2[nH]ccc12)c1ccc(Cl)cc1F

InChI Key InChIKey=QMWQDMRIHHKCTR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 676764   

TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM676764(methyl 2-(4-chloro-2-fluorophenyl)-2-(3-(methyl(7H...)
Affinity DataIC50: 25.1nMAssay Description:The objective of this study was to assess the activity of novel JAK inhibitors measuring the capability of compounds to inhibit JAK1 kinase activity ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2024
Entry Details
Go to US Patent