BDBM678087 N-[1- (cyclobutylmethyl)- 1H-pyrazol-4-yl]- 6-(4,5,6,7- tetrahydropyrazolo [1,5-a]pyridin-3- yl)pyridine-2- carboxamide::US20240174679, Example 9-13

SMILES O=C(Nc1cnn(CC2CCC2)c1)c1cccc(n1)-c1cnn2CCCCc12

InChI Key InChIKey=JXGBRKQVSNBHPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 678087   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM678087(US20240174679, Example 9-13 | N-[1- (cyclobutylmet...)
Affinity DataIC50: 20.9nMAssay Description:IC50 (half-maximal inhibitory concentration) represents the concentration of inhibitor required to inhibit LRRK2 kinase activity by 50%. Assays were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2024
Entry Details
US Patent